In a case study by Vidal et al. (2025), a 57-year-old male with a history of mantle cell lymphoma (MCL) experienced a recurrence of the disease seven years after initial treatment and remission. The recurrence manifested as a 2 × 3 cm nodule in the right buccal mucosa, which is the inner cheek area. The patient reported symptoms including dysphagia, which is difficulty swallowing, and noted that the nodule had developed rapidly.
Diagnostic efforts included a guided puncture biopsy, which revealed an oval lesion with soft tissue density in contact with the oral mucosa. The differential diagnosis considered the possibility of a salivary gland tumor or a lymphoma recurrence. This case underscores the importance of ongoing vigilance for signs of MCL recurrence, even years after successful treatment.
Clinical Trials
This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks: