Mantle Cell Lymphoma Insights

This week's must-know community updates, latest research & events

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Latest Research

Recent research has explored the efficacy and safety of tirabrutinib monotherapy in patients with B-cell lymphomas, including mantle cell lymphoma. This study aims to analyze data on how well tirabrutinib works for these conditions. While specific findings from the study are not detailed in the provided information, it is part of broader efforts to find effective treatments for B-cell lymphomas, which include mantle cell lymphoma. Tirabrutinib is a type of medication that targets specific pathways involved in cancer cell growth.

The study by Wang et al. (2025) contributes to ongoing research into treatments for mantle cell lymphoma and other B-cell lymphomas. As treatments evolve, they offer hope for improving remission periods and managing these conditions more effectively. Further details from the study could provide insights into the potential benefits and limitations of tirabrutinib for patients with these cancers.

Clinical Trials

This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks:
Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's Lymphoma
Study Type
Phase I
Location
3 countries
Age Range
18+ Years
Enrollment
165
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
Study Type
Phase I
Location
2 countries
Age Range
18+ Years
Enrollment
168
Cytokine-Treated Veto Cells in Treating Patients with Hematologic Malignancies Following Stem Cell Transplant
Study Type
Phase II
Location
Texas
Age Range
12 - 75 Years
Enrollment
24
A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies
Study Type
Phase II
Location
15 countries
Age Range
18+ Years
Enrollment
621

Community News

The Leukemia & Lymphoma SocietyThe Leukemia & Lymphoma SocietyMar 18, 2025

Kids deserve better than a one-size-fits-all approach to blood cancer treatment. 🗣️

That’s why The Dare to Dream Project is investing $175 million to transform care with safer, more effective options. From breakthrough clinical trials to vital support services, we’re daring to create a world where kids not only survive but thrive. Learn more 👉 https://bit.ly/4c36qrJ#WeDareToDream4Kids

Lymphoma ActionLymphoma ActionMar 19, 2025

“I remember that time clearly. We had to wait a couple of weeks between the biopsies… I tried to keep as positive as possible and really hoped that everything would be fine as I could see that everyone around me was struggling.

The third biopsy revealed that I had diffuse large B-cell lymphoma. It felt like the diagnosis had been a long time coming, but I didn’t know how to react to this. I did not know what lymphoma was. I had never thought I would have to face cancer and being a blood cancer seemed very difficult to understand. But I did feel like having a diagnosis now meant that something could now be done.

I had six rounds of R-CHOP chemotherapy which was given as a day patient. Although it was quite a distance from home, I was there for a long day and was very comfortable there; it almost felt like a second home. There was plenty to do and I was around people my own age, which helped me meet others going through a similar thing. This helped give me confidence throughout treatment being there with others like me, sharing our experience and helping each other.” Georgia

Georgia talks about her experience of diagnosis and treatment of diffuse large B-cell lymphoma: www.lymphoma-action.org.uk/Georgia-0

#Lymphoma#BloodCancer#DLBCL

#NonHodgkinsLymphoma

Lymphoma Action Post
Lymphoma Research FoundationLymphoma Research FoundationMar 20, 2025

Dr. Gita Thanarajasingam (Mayo Clinic) is pioneering a patient-centered approach to lymphoma treatment. With a global upbringing and a deep passion for medicine, she has dedicated her career to improving treatment tolerability and understanding the full patient experience.

Discover more about her work and her efforts to improve the patient journey in the latest issue of Pulse: https://lymphoma.org/news/helping-patients-with-lymphoma-live-not-only-longer-but-better/

Lymphoma Research Foundation Post